Figure 3.
Experiment 2 plasma measures and brain gene expression in adult males and females 3 hours after an intragastric (i.g.) intubation of vehicle (VEH) or 5 g/kg ethanol (EtOH). Plasma measures shown include (A) ethanol concentrations and (B) corticosterone. Gene expression outcomes in the hippocampus and amygdala are shown for (C, G) Interleukin-6 - IL-6 gene expression; (D, H) Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha - IκBα; (E, I) Interleukin-1β - IL-1β; and (F, J) Tumor necrosis factor alpha - TNFα. Significant effects of Drug are indicated with a pound sign (#) above the EtOH groups indicating significant difference form the VEH groups, and letters indicate differences divulged by post hoc testing of a significant interaction (groups that share a letter in common did not differ statistically, whereas differences between groups are indicated by letters that do not match).