Table 2.

Results of baseline MRI features separating resilient from non‐resilient UHR individuals (models B) and quantitative predictions of long‐term functional and clinical outcome (models C)

Binary models (B)	Sensitivity (%)	Specificity (%)	Average accuracy (%)	P
Cortical Volume	71	67	69	0.015*
Surface area	47	42	44	n.s.
Cortical thickness	47	50	49	n.s.
Gyrification	69	78	73	0.016*
Subcortical volume	59	75	67	0.047*
SIPS Disorganization (all)	76	71	74	0.001**
SIPS Disorganization (gyrification subset)	75	78	76	0.002**
Gyrification + Subcortical Volume	69	78	73	0.021*
SIPS Disorganization + Gyrification	69	83	76	0.005**
SIPS Disorganization + Subcortical Volume	76	71	74	0.013*
SIPS Disorganization + Cortical Volume	59	75	67	0.002**
SIPS Disorganization + Gyrification + Subcortical Volume	69	94	82	0.003**
Continuous models (C)	r	P
Model C1: mGAF score at 6‐yr follow‐up
Gyrification	0.382	0.048*
Subcortical Volume	0.424	0.008**
SIPS Disorganization + Gyrification + Subcortical Volume	0.327	n.s.
Model C2: SIPS Positive score at 6‐yr follow‐up
Cortical thickness	0.258	n.s.
Model C3: SIPS Negative score at 6‐yr follow‐up
Subcortical Volume	0.349	0.048*
Model C4: SIPS Disorganization score at 6‐yr follow‐up
Gyrification	0.411	0.044*
Subcortical Volume	0.342	n.s.
SIPS Disorganization + Gyrification + Subcortical Volume	0.378	n.s.

Notes: ^aSubgroups are based on functional outcome at 6‐year follow‐up.

UHR = Individuals at ultra‐high risk for psychosis; mGAF = Modified Global Assessment of Functioning; SIPS = Structured Interview for Prodromal Symptoms; n.s. = non‐significant.

*P < 0.05.

**P < 0.01.