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. 2016 Oct 11;38(2):923–937. doi: 10.1002/hbm.23428

Table 2.

Correlations between rsFC post‐training changes (Rest 2–Rest 1) and the boost of performance

MNI coordinates (mm)
Location of maxima x y z Peak r‐scores P‐value
Young participants Young Old
L inferior frontal gyrus −54 24 14 −0.84 −0.2
L superior parietal lobule (BA5) −4 −61 70 0.79 0.6
R middle frontal gyrus (DLPFC) 39 24 50 0.83 0.25
R inferior temporal gyrus 50 −41 −25 −0.79 0.33 #
R middle temporal gyrus 66 −26 −5 −0.80 0.1 #
Old participants Old Young
L caudate nucleus −10 −1 15 0.79 −0.19 #
L lingual gyrus (V2) −4 −91 −11 −0.84 0.044 #
L paracentral lobule 11 −11 80 −0.81 −0.046
R cerebellum (lobule V) 20 −34 −22 −0.82 −0.26
R superior temporal gyrus 66 −6 1 0.84 0.02 #

Brain regions where rsFC changes from Rest 1 to Rest 2 significantly correlated with the boost of performance at retest, in young (A) and old (B) participants. MNI coordinates locate the correlation peak in each region of significance. Peak r scores show the correlation coefficients in the group for which a significant correlation has been identified (young or old) and the corresponding values in the other group (old or young). Positive (respectively, negative) values indicate that post‐training rsFC increases (respectively, decreases) are associated with a stronger boost effect. The P‐values assess the differences between young and old individuals in the peak r score and no group differences survive to correction for multiple comparisons (all P > 0.0009; # indicates P uncorr < 0.01). DLPFC, dorsolateral prefrontal cortex; BA5, somatosensory association cortex; V2, secondary visual cortex.