Figure 1.

The pipeline of the tract‐based analysis using predefined tracts. With our TABS, we built a population‐specific diffusion tensor template and sensitively investigated the microstructural properties along the region of interest fibers to determine more characteristics. To provide spatial normalization for the analysis of diffusion values at corresponding locations, the tensor properties in the subjects' native space (a) were integrated to create a population‐specific tensor template (b). Based on the whole‐brain tractography maps in the population space (c), the tract of interest was selected and converted into a continuous function (d). Fibers in the population space were warped back into the individual's native space (e) to collect the diffusion measure (f). [Color figure can be viewed at http://wileyonlinelibrary.com]