Table 3.

Correlations of clinical variables with functional and structural neuroimaging parameters (i.e., ¹²³I‐ioflupane uptakes and MRI graph metrics, respectively) in all 63 patients with Parkinson's disease

	Disease duration		UPDRS‐ME		Tremor subscore		Nontremor subscore (B+R)		Axial subscore
	rho	P value	rho	P value	rho	P value	rho	P value	rho	P value
123I‐ioflupane uptakes
Specific/nonspecific ratios
LAS putamen	−0.42	0.006	−0.45	0.006	0.13	0.47	−0.52	0.003	−0.32	0.03
MAS putamen	−0.43	0.006	−0.40	0.006	0.08	0.65	−0.48	0.006	−0.24	0.15
LAS caudate nucleus	−0.36	0.02	−0.31	0.03	0.23	0.17	−0.44	0.006	−0.22	0.18
MAS caudate nucleus	−0.35	0.02	−0.30	0.06	0.19	0.18	−0.41	0.006	−0.23	0.16
LAS striatum	−0.39	0.01	−0.48	0.006	0.10	0.57	−0.54	0.003	−0.35	0.02
MAS striatum	−0.37	0.01	−0.33	0.03	0.14	0.47	−0.42	0.003	−0.25	0.13
MRI network metrics
Anatomical connectivity indices
MAS globus pallidus–substantia nigra tract	0.08	0.72	0.13	0.47	0.37	0.02	0.02	0.95	0.21	0.18
MAS globus pallidus–thalamus tract	−0.29	0.06	−0.31	0.06	0.05	0.78	−0.33	0.03	−0.10	0.57
MAS putamen–precentral cortex tract	−0.40	0.006	−0.11	0.57	0.29	0.06	−0.19	0.18	−0.09	0.64
MAS thalamus–precentral cortex tract	−0.01	1.0	−0.22	0.18	0.17	0.34	−0.21	0.18	0.16	0.34
MAS caudate nucleus–supplementary motor area trct	0.03	0.87	−0.07	0.72	0.35	0.02	−0.27	0.08	−0.08	0.72
Weighted nodal efficiency values
MAS globus pallidus	−0.19	0.18	−0.21	0.18	−0.43	0.006	−0.05	0.77	−0.11	0.57
MAS putamen	0.17	0.34	0.20	0.18	−0.10	0.57	0.14	0.47	0.24	0.16
MAS supplementary motor area	−0.06	0.78	−0.10	0.64	−0.22	0.18	−0.01	1.0	−0.06	0.72
MAS substantia nigra	−0.09	0.65	0.09	0.64	0.10	0.64	−0.01	0.95	0.06	0.78
LAS substantia nigra	−0.05	0.77	0.03	0.86	0.07	0.72	0.01	1.0	−0.01	1.0

rho = Spearman's correlation coefficient. Significant P values corrected for multiple comparisons (false discovery rate correction) are indicated in bold.