Table 1.
MDMR results (PseudoF, PseudoR 2, and P value) for the full set of independent variables [Model 1. Eight predictors: brain volume, age, fluid reasoning (Gf), crystallized ability (Gc), and spatial ability (Gv), working memory capacity (WMC), attention control (ATT), and processing speed (PS)] and only for the significant predictors in Model 1 [Model 2. Three significant predictors (Gf, Gc, and Gv) when the whole‐brain connectivity profiles were set as dependent variable; and five predictors (brain volume, age, Gf, Gc, and Gv) when the reduced connectivity profiles were set as dependent variable]
Predictor | Whole‐brain profile | Reduced profile | ||||
---|---|---|---|---|---|---|
PseudoF | PseudoR 2 | P value | PseudoF | PseudoR 2 | P value | |
Model 1 | ||||||
Brain volume | 1.5958 | 0.0169 | 0.092 | 7.1730 | 0.0652 | 0.001b |
Age | 1.0712 | 0.0113 | 0.316 | 2.0409 | 0.0185 | 0.040a |
Gf | 2.5394 | 0.0269 | 0.014a | 7.5708 | 0.0689 | 0.001b |
Gc | 3.0281 | 0.0321 | 0.005b | 7.6015 | 0.0691 | 0.001b |
Gv | 2.0812 | 0.0220 | 0.025a | 5.4767 | 0.0498 | 0.001b |
WMC | 0.6423 | 0.0068 | 0.869 | 1.2468 | 0.0113 | 0.271 |
ATT | 0.5480 | 0.0058 | 0.962 | 1.5776 | 0.01434 | 0.130 |
PS | 0.7000 | 0.0074 | 0.774 | 1.8798 | 0.0170 | 0.073 |
Total | 1.1605 | 0.0984 | 0.169 | 3.1190 | 0.2269 | 0.001b |
Model 2 | ||||||
Brain volume | 5.9894 | 0.0560 | 0.001b | |||
Age | 2.0533 | 0.0192 | 0.041a | |||
Gf | 2.7894 | 0.0295 | 0.004b | 8.3472 | 0.0781 | 0.001b |
Gc | 2.6296 | 0.0278 | 0.010a | 6.1217 | 0.0573 | 0.001b |
Gv | 1.4267 | 0.0150 | 0.108 | 4.0102 | 0.0375 | 0.001b |
Total | 1.5144 | 0.0480 | 0.033a | 3.7551 | 0.1758 | 0.001b |
PseudoR 2 was computed using a type II sum of squares strategy. The statistical significance of each predictor (P value) was calculated using permutation methods (1,000 permutations were run to built the null distribution). They represent the proportion of times the simulated PseudoFs (computed on random datasets) exceed the empirical PseudoF.
Significant at alpha = 0.05.
Significant at alpha = 0.01.