Table 1.
SERT BPND by region of interest
| Region of interest | HC | ADHD | p‐value |
|---|---|---|---|
| Anterior cingulate cortex | 0.318 ±0.071 | 0.278 ±0.076 | 0.066 |
| Amygdala | 1.025 ±0.158 | 0.958 ±0.181 | 0.183 |
| Dorsal raphe nucleus | 3.522 ±0.653 | 3.463 ±0.526 | 0.697 |
| Hippocampus | 0.605 ±0.127 | 0.563 ±0.118 | 0.194 |
| Insula | 0.558 ±0.103 | 0.518 ±0.101 | 0.085 |
| Precuneus | 0.240 ±0.052 | 0.198 ±0.070 | 0.723 |
| Posterior cingulate cortex | 0.246 ±0.078 | 0.228 ±0.085 | 0.433 |
| Striatum | 1.748 ±0.248 | 1.603 ±0.209 | 0.029* |
| Thalamus | 1.880 ±0.266 | 1.772 ±0.256 | 0.096 |
Mean SERT BPND and standard deviations are listed from automated AAL, including manually delineated ROI dorsal raphe nuclei for patients with ADHD and HC.
*Marks significant differences between patients with ADHD and HC, though, after Bonferroni correction for multiple comparisons, differences are not significant different.
AAL: anatomical labelling atlas; ADHD: attention deficit/hyperactivity disorder; HC: healthy control subjects; SERT BPND: serotonin transporter binding potential; ROIs: regions of interest.