Table 1.
Cortical regions with CH‐associated thickness changes (Fig. 2) [Color table can be viewed at http://wileyonlinelibrary.com]
| Index | DK atlas | BA | t value | Coordinates (x,y,z) | Size (mm2) | ||
|---|---|---|---|---|---|---|---|
| ° 1 | L medial orbitofrontal cortex | L anterior cingulate cortex (ACC) (BA24) | 4.5212 | −6.4 | 16.0 | −16.2 | 126.43 |
| 2 | L inferior parietal cortex | L multisensory association area (BA39) | 2.4505 | −39.6 | −68.2 | 44.9 | 100.93 |
| ° 3 | L precentral gyrus | L premotor cortex (BA6) | −2.4185 | −48.7 | −1.7 | 40.6 | 229.64 |
| ° 4 | L posterior cingulate cortex (PCC) | L PCC (BA23) | 2.7635 | −4.0 | −12.6 | 33.1 | 282.06 |
| 5 | L middle temporal gyrus | L multimodal posterior area (BA21) | −2.4923 | −59.0 | −15.1 | −23.8 | 164.05 |
| ° 6 | L lingual gyrus | L visual association area (BA18) | −2.4268 | −25.1 | −64.0 | 1.1 | 225.26 |
| ° 7 | R rostral middle frontal gyrus | R prefrontal cortex (BA10) | −2.8411 | 22.7 | 56.4 | 16.2 | 271.50 |
| ° 8 | R superior parietal cortex | R secondary sensorimotor cortex (BA7) | −3.5559 | 33.5 | −44.7 | 48.9 | 112.13 |
| 9 | R inferior parietal cortex | R multisensory association area (B39) | 2.3254 | 47.6 | −53.8 | 33.2 | 122.50 |
| 10 | R postcentral gyrus | R primary somatosensory cortex (S1) | 2.7027 | 5.4 | −38.1 | 74.0 | 141.30 |
| ° 11 | R lateral occipital cortex | R secondary visual cortex (V2) | −2.9200 | 30.0 | −80.8 | −9.1 | 421.42 |
| ° 12 | R cuneus cortex | R primary visual cortex (V1) | −2.8644 | 10.1 | −69.3 | 17.9 | 328.96 |
Note: “°” indicates regions survived the multiple comparison corrections (Monte Carlo simulation, P < 0.05, FreeSurfer). Regions in left (L) or right (or R) hemispheres are highlighted by blue or red background, respectively. x‐y‐z coordinates are in MNI space. Positive and negative numbers indicate cortical thickening and thinning in CH patients, respectively.