Table 2.

Estimation of the marginal geometric mean difference in sumPCBs, PFAS, As, and Hg concentrations in mothers and children from a hypothetical intervention scenario of weekly fish consumption.

Pollutants	Exposed/total ($n$/$N$)	Intervention scenario
		$\mathrm{\Psi }$	95% CI
Women (pregnancy)a
SumPCBs (ng/g lipid)	347/516	1.13	$-15.19$, 17.46
PFOA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	377/722	$-0.13$	$-0.44$, 0.17
PFNA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	377/722	$-0.17$	$-0.26$, $-0.07$
PFUnDA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	340/524	$-0.02$	$-0.04$, 0.00
PFOS ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	377/722	0.83	$-0.01$, 1.68
PFHxS ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	377/722	0.04	$-0.08$, 0.15
As ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	256/409	$-2.08$	$-2.62$, $-1.54$
Hg ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	289/590	$-1.02$	$-1.39$, $-0.65$
Children (5–12 y of age)b
SumPCBs (ng/g lipid)	817/1,265	1.63	$-1.09$, 4.36
PFOA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	835/1,286	$-0.04$	$-0.11$, 0.04
PFNA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	835/1,286	$-0.05$	$-0.13$, 0.03
PFUnDA ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	835/1,286	$-0.03$	$-0.05$, $-0.02$
PFOS ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	835/1,286	$-0.46$	$-0.71$, $-0.21$
PFHxS ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	835/1,286	0.05	$-0.21$, 0.30
As ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	833/1,283	$-0.81$	$-1.19$, $-0.44$
Hg ($\mathrm{\mu }\mathrm{g}/\mathrm{L}$)	833/1,283	$-0.73$	$-0.91$, $-0.55$

Intervention scenario: $\mathrm{A}=1$: following the dietary recommendation for weekly fish consumption (women: up to 3 meals/week and children: up to 2 meals/week); $\mathrm{A}=0$: exceeding the dietary recommendation for weekly fish consumption. As, arsenic; BiB, Born in Bradford cohort; CI, confidence interval; Hg, mercury; KANC, Kaunas Cohort; PFHxS, perfluorohexane sulfonate; PFNA, perfluorononanoate; PFOA, perfluorooctanoate; PFOS, perfluorooctane sulfonate; PFUnDA, perfluoroundecanoate; SumPCBs, summarized concentration of polychlorinated biphenyls; $\mathrm{\Psi }$: marginal geometric mean difference between exposed and unexposed.

^aModels are adjusted for all food groups and for cohort, maternal age, educational level, parity, prepregnancy body mass index, gestational weight gain, active smoking during pregnancy, and year of delivery. Women from KANC and BiB are not included.

^bModels are adjusted for all food groups and for cohort, age, body mass index, Family Affluence Score, year of birth, and firstborn.