Table 3.
Peak MNI coordinates for contrast comparisons analysis between PAG subregions
Peak voxel, MNI coordinates | ||||
---|---|---|---|---|
Region | Z‐max | x | y | Z |
Ventrolateral > lateral | ||||
Right | ||||
PAG | 8.12 | 4 | −34 | −16 |
Hypothalamus/thalamus | 5.57 | 0 | −30 | −2 |
L putamen | 4.58 | −26 | −4 | 8 |
R caudate | 4.46 | 20 | −2 | 14 |
L thalamus | 4.26 | −12 | −8 | 4 |
Upper pons | 4.11 | 4 | −36 | −24 |
Lower pons | 3.93 | −2 | −38 | −36 |
Medulla | 3.92 | 4 | −44 | −54 |
L insulaa | 3.03 | −40 | 16 | −2 |
Left | ||||
PAG/VTA/dorsal raphe | 7.89 | 0 | −32 | −16 |
R frontal pole BA9 | 4.54 | 28 | 40 | 32 |
R middle frontal gyrus BA9 | 4.2 | 32 | 26 | 30 |
L cerebellum | 3.96 | −30 | −68 | −36 |
R angular gyrus (TPJp) | 3.87 | 42 | −50 | 34 |
R supramarginal gyrus (IPL) | 3.81 | 56 | −32 | 42 |
R thalamus | 3.56 | 6 | −16 | −4 |
R upper pons/central gray | 3.55 | 4 | −36 | −26 |
R upper/mid pons | 3.54 | 4 | −38 | −30 |
Lateral > ventrolateral | ||||
Right | ||||
L precuneus cortex | 4.35 | −10 | −56 | 56 |
L SPL BA5/S1 BA2 | 4.18 | −20 | −44 | 50 |
R/L occipital pole | 3.59 | −4 | −90 | 10 |
L S1 | 3.53 | −32 | −40 | 50 |
R/L intracalcarine cortex | 3.49 | 10 | −86 | 12 |
L supramarginal gyrusa | 3.33 | −52 | −34 | 50 |
Left | ||||
R/L occipital pole | 4.38 | 14 | −90 | 20 |
R/L superior temporal gyrus | 4.58 | −52 | −40 | 6 |
R/L M1 BA4/SPL | 3.99 | −6 | −36 | 56 |
R S1 BA3/S2 | 3.91 | 52 | −8 | 22 |
R/L planum temporal (TPJa) | 3.78 | −40 | −40 | 14 |
R/L superior temporal gyrus | 3.5 | −64 | −30 | 2 |
R/L middle temporal gyrus | 3.42 | −54 | −56 | 4 |
R lateral occipital cortex | 3.43 | 30 | −76 | 18 |
R premotor cortex BA6 | 3.33 | 60 | 4 | 30 |
R S2 | 3.19 | 56 | −10 | 14 |
Ventrolateral > dorsolateral | ||||
Right | ||||
R PAG | 9.39 | 4 | −30 | −12 |
R parahippocampal gyrus | 5.85 | 22 | −36 | −14 |
R/L cerebellum | 5.59 | −12 | −50 | −22 |
R superior temporal gyrus | 3.8 | 54 | −22 | −2 |
R middle temporal gyrus | 3.65 | 62 | −26 | −6 |
L occipital pole/lateral occipital cortex | 3.56 | −26 | −92 | −2 |
L lingual gyrus | 3.36 | −20 | −84 | 0 |
Left | ||||
L PAG | 10 | −2 | −32 | −12 |
R parahippocampal gyrus | 5.63 | 22 | −36 | −14 |
R medulla | 4.72 | 2 | −42 | −54 |
R upper pons | 4.55 | 6 | −34 | −24 |
R mid pons | 4.51 | 4 | −38 | −34 |
R temporal fusiform cortex/hippocampus | 4.3 | 34 | −28 | −20 |
Dorsolateral > ventrolateral | ||||
Right | ||||
PAG | 11 | 0 | −32 | −4 |
R/L thalamus | 6.41 | 0 | −28 | 6 |
Premotor cortex BA6 (SMA) | 3.64 | 10 | 2 | 56 |
Cingulate gyrus (pMCC) | 3.43 | −4 | −32 | 46 |
R M1 BA4 | 3.28 | 4 | −36 | 58 |
R SPL/M1a | 3.09 | 2 | −38 | 52 |
Left | ||||
PAG | 11.2 | 0 | −32 | −4 |
R/L thalamus | 6.38 | −2 | −26 | 6 |
R premotor cortex BA6 (SMA) | 4.05 | 10 | 0 | 58 |
L superior frontal gyrus | 3.89 | −22 | 10 | 58 |
R/L SPL/precuneous cortex | 3.71 | 12 | −20 | 58 |
L hippocampusa | 3.40 | −10 | −40 | 2 |
L M1a | 3.27 | −10 | −32 | 68 |
Lateral > dorsolateral | ||||
Right | ||||
PAG | 6.86 | 8 | −34 | −6 |
R/L occipital pole/intracalcarine cortex | 4.31 | −2 | −90 | 12 |
R occipital fusiform gyrus/lingual gyrus | 4.1 | 22 | −68 | −8 |
R lateral occipital cortex | 4.61 | 50 | −76 | 4 |
R middle temporal gyrus | 3.81 | 70 | −32 | −10 |
R superior temporal gyrus/lateral occipital cortex | 3.6 | 58 | −34 | 4 |
S1 BA1‐3 | 4.22 | 50 | −28 | 54 |
R/L supramarginal gyrus/SPL BA7 | 4 | 40 | −28 | 36 |
L S2/insular gyrus | 4.32 | −42 | −30 | 20 |
R premotor cortex/M1a | 3.31 | 34 | −28 | 70 |
Left | ||||
L PAG | 7.68 | −6 | −32 | −10 |
R lingual gyrus | 4.61 | 16 | −44 | −10 |
R/L occipital pole | 4.54 | 14 | −90 | 22 |
L substantia nigra | 4.5 | −14 | −26 | −12 |
R temporal occipital fusiform cortex | 4.37 | 28 | −56 | −10 |
R/L middle temporal gyrus | 4.05 | −48 | −26 | −14 |
R/L superior temporal gyrus | 4.05 | −50 | 0 | −20 |
L planum temporal | 3.88 | −40 | −40 | 12 |
L mid‐insulaa | 3.90 | 36 | −8 | 14 |
L supramarginal gyrusa | 3.58 | −60 | −48 | 14 |
Dorsolateral > lateral | ||||
Right | ||||
PAG | 8.65 | 0 | −32 | −2 |
R/L thalamus | 5.78 | −4 | −16 | 8 |
R premotor cortex BA6 (SMA) | 3.85 | 6 | −4 | 56 |
R paracingulate gyrus | 3.56 | 4 | 8 | 48 |
Left | ||||
R PAG | 7.24 | 0 | −34 | −2 |
R/L thalamus | 5.08 | −10 | −12 | 12 |
R frontal pole | 4.59 | 28 | 40 | 32 |
R middle frontal gyrus | 4.37 | 34 | 32 | 42 |
R premotor cortex/SMA | 4.23 | 6 | −8 | 62 |
L/R putamena | 4.88 | −24 | −6 | 10 |
L/R caudatea | 4.33 | −16 | 0 | 18 |
L insulaa | 3.50 | −34 | 6 | 6 |
L/R amygdalaa | 2.91 | 26 | 0 | −12 |
MNI coordinates (in mm) are reported at maximum peak and are corrected for multiple comparisons using family‐wise error correction at Z > 2.3 and P < 0.05. BA, Brodmann area; IPL, inferior parietal lobule; L, left; M1, primary motor cortex; PAG, periaqueductal gray; R, right; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; SMA, supplementary motor area; SPL, superior parietal lobule; TPJa, temporoparietal junction, anterior division; TPJp, temporoparietal junction, posterior division.
Subcluster peak coordinates.