Table 3.
ANOVA with CST WM lesions as grouping variable (groups 1–4)
Controls | Controls | VP/VLBW | VP/VLBW | ANOVA | |
---|---|---|---|---|---|
1. Without CST lesions | 2. With CST lesions | 3. Without CST lesions | 4. With CST lesions | ||
n = 50 | n = 3 | n = 38 | n = 18 | ||
Age, years | 27.09 (0.78) | 27.11 (1.07) | 26.91 (0.58) | 26.86 (0.67) | F(3,105) = 0.7071, P = 0.5499 |
Gestational age at birth, weeks | 39.76 (0.94) | 37.67 (1.15) | 30.47 (1.87) | 30.17 (1.89) | F(3,105) = 349.1, P < 0.001* |
1‐2: P = 0.09 | |||||
1‐3: P < 0.001* | |||||
1‐4: P < 0.001* | |||||
2‐3: P < 0.001* | |||||
2‐4: P < 0.001* | |||||
3‐4: P = 0.891 | |||||
Birth weight, grams | 3356 (473) | 3007 (627) | 1321 (311) | 1363 (331) | F(3,105) = 222.9, P < 0.001* |
1‐2: P = 0.47 | |||||
1‐3: P < 0.001*1‐4: P < 0.001* | |||||
2‐3: P < 0.001* | |||||
2‐4: P < 0.001* | |||||
3‐4: P = 0.98 | |||||
FA | 0.50 (0.02) | 0.50 (0.05) | 0.50 (0.02) | 0.51 (0.02) | F(3,105) = 0.6359, P = 0.593 |
AD (10−3s/mm2) | 1.16 (0.03) | 1.19 (0.05) | 1.19 (0.03) | 1.21 (0.05) | F(3,105) = 8.688, P < 0.001 |
1‐2: P = 0.689 | |||||
1‐3: P = 0.017* | |||||
1‐4: P < 0.001* | |||||
2‐3: P = 1 | |||||
2‐4: P = 0.688 | |||||
3‐4: P = 0.077 | |||||
MD (10−3s/mm2) | 0.72 (0.02) | 0.74 (0.02) | 0.74 (0.02) | 0.75 (0.03) | F(3,105) = 6.839, P < 0.001* |
1‐2: P = 0.756 | |||||
1‐3: P = 0.032* | |||||
1‐4: P < 0.001* | |||||
2‐3: P = 1 | |||||
2‐4: P = 0.778 | |||||
3‐4: P = 0.182 | |||||
RD (10−3s/mm2) | 1.00 (0.04) | 1.02 (0.07) | 1.02 (0.05) | 1.04 (0.07) | F(3,105) = 2.23, P = 0.089 |
When the overall ANOVA indicated a significant effect, post hoc comparisons (all combinations of subgroups) using the Tukey HSD test have also been performed. The post hoc contrasts 1–3 and 1–4 denote the difference between control subjects without visible CST lesions and VP/VLBW without (1–3), respectively VP/VLBW with CST lesions (1–4). Contrast 3–4 shows the influence of CST lesions within the VP/VLBW group. Mean (standard deviation) are also provided and significant differences are marked with asterisk.