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. 2016 Mar 7;37(6):2263–2275. doi: 10.1002/hbm.23171

Table 4.

Brain areas showing positive modulation in BOLD amplitude with CO2 level in thermal tasters (TTs) and thermal non tasters (TnTs)

Area Side MNIa Z‐score P‐value Cluster sizeb, k
Thermal taster (TT)
SII
L −62, −28,16 5.41 <0.001 51
R 64, −14, 8 3.34 0.003 26
Thermal non‐ taster (TnT)
Primary Somatosensory Cortex (SI)* R

62, −12, 42

54, −16, 22

58, −20, 26

3.59

3.25

3.23

<0.001

<0.001

0.001

797
L −52, −14, 46 3.52 <0.001 sub
Secondary somatosensory cortex (SII)* R

62, −26, 18

68, −28, 8

4.55

3.89

<0.001

<0.001

sub
Rolandic operculum* R 56, 0, 6 4.55 <0.001 sub
L −56, 2, 14 3.54 <0.0001 44
ACC* R 2, 0,50 3.31 <0.0001 312
L −6, −10, 48 3.34 <0.0001 sub
Precentral gyrus* R 60, −2, 42 3.58 <0.0001 sub

R, right hemisphere; L, left hemisphere; MNI, Montreal Neurological Institute.

a

Peak voxel coordinates given in MNI space (x,y,z).

b

Reported clusters threshold at P < 0.005, uncorrected for multiple comparisons, with a cluster extent threshold k > 20 voxels, and “sub” indicates sub‐cluster level, Asterisks indicate areas activated with FDR corrected P < 0.05.