Table 1.
| Study | Year | MDD/HC (N) | Age (Mean) | Sex M/F | Age onset (Years) | State | Scanner (Tesla) | GM type | Analysis | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| Abe et al. | 2010 | 21/42 | 48.1 | 11/10 | 42.1 |
Current Remitted |
1.5 | Volume | SPM5 |
↓GMV R: PHG/H/ACC/sTG L: PL/OL R/L: mFG |
| Amico et al. | 2011 | 33/64 | 32 | 19/14 | 28.7 | Current | 1.5 | Volume | SPM5 |
↓GMV L: dmPFC/ACC R: C |
| Arnone et al. | 2013 | 39/66 | 36.3 | 12/27 | 22 | Current | 1.5 | Volume | SPM8 |
↓GMV R/L: H |
| Cheng et al. | 2010 | 68/68 | 29.91 | 21/47 | 28.94 | Current | 1.5 | Volume | SPM5 |
↓GMV R: SMA |
| Colloby et al. | 2011 | 38/30 | 74.1 | 11/27 | 51.8 |
Current Remitted |
3 | Volume | SPM8 | No difference |
| Kim et al. | 2008 | 22/25 | 38.5 | 0/22 | NS | Current | 1.5 | Volume | SPM2 |
↓GMV R/L: T, C |
| Koolschijn et al. | 2010 | 28/38 | 64.04 | 0/28 | 33.04 | Current | 1.5 | Density | ANIMAL | No difference |
| Lee et al. | 2011 | 47/51 | 46 | 5/42 | NS | Current | 1.5 | Density | SPM2 |
↓GMD R/L: H/FG/A/LG/Ins/sTG/T/CG/Cer |
| Perico et al. | 2011 | 20/94 | 29.9 | 5/15 | NS | Current | 1.5 | Volume | SPM2 |
↓GMV R/L: dLPFC |
| Salvadore et al. | 2011 | 58/107 | 38.8 | 37/21 | NS | Current | 3 | Volume | SPM5 |
↓GMV L: iFG R: mFG/sFG |
| Van Tol et al. | 2010 | 68/65 | 37.16 | 24/44 | 25.62 |
Current Remitted |
3 | Volume | SPM5 |
↓GMV R/L: rdACC R: iFC |
| Wagner et al. | 2011 | 30/30 | 37.6 | 5/25 | 31.6 | Current | 1.5 | Density | SPM2 |
↓GMD R/L: C/sC/H/A L: sFG/OF R: iFG |
Studies included in the meta‐analysis. GMV/GMD, grey matter volume/density; C, caudate nucleus; PHG, parahippocampal gyrus; H, hippocampus; A, amygdala; ACC, anterior cingulate cortex; rdACC, rostro‐dorsal ACC; CG, cingulate gyrus; Cer, cerebellum; sC, subgenual cortex; MB, midbrain; iFC, inferior frontal cortex; dmPFC, dorso‐medial prefrontal cortex; dLPFC, dorso‐lateral prefrontal cortex; Ins, Insula; iFG, inferior frontal gyrus; FG, fusiform gyrus; mFG, middle frontal gyrus; sFG, superior frontal gyrus; iFG, inferior frontal gyrus; sTG, superior temporal gyrus; PL, parietal lobe, LG, lingual gyrus; OL, occipital lobe; SMA, supplementary motor area; T, thalamus.