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. 2019 Nov 20;14(11):e0225449. doi: 10.1371/journal.pone.0225449

Fig 4. Gastroparesis is a novel, GST-sensitive biomarker of acute acrylamide toxicity.

Fig 4

Stomach enlargement of male wild-type (A) and ΔPMT (B) mice 24 hours after a 50 mg/kg dose acrylamide exposure. Stomachs of male wild-type (C) or ΔPMT (D) mice treated with PBS control are provided for reference. Stomach weights were measured after a single 50 mg/kg (E) and 25 mg/kg (F) dose of exposure. (G) Stomach weights of male mice after a single 50 mg/kg exposure to glycidamide. All measurements were taken 24 hours after the injection. ACR = acrylamide, GLY = glycidamide. Data represent means ± SEM; n = 9–18 (E-F) or 6 (G). Data analyzed by one-way ANOVA corrected for multiple comparisons; * p < 0.05; *** p < 0.001; **** p < 0.0001.