Table 2. Drug resistance among 2269 patients with MDR-TB and XDR-TB.
| Drug | Resistant | MDR-TB | XDR-TB | p-value † |
|---|---|---|---|---|
| n/N* (%) | n/N* (%) | n/N* (%) | ||
| First-line drugs | ||||
| Isoniazid | 2269/2269 (100.0) | |||
| Rifampicin | 2269/2269 (100.0) | |||
| Ethambutol | 862/2169 (39.7) | 767/2031 (37.8) | 95/138(68,8) | <0.001 |
| Pyrazinamide | 703/1008 (69.7) | 659/958 (68.8) | 44/50 (88) | 0.004 |
| Streptomycin | 949/2160 (43.9) | 858/2022 (42.4) | 91/138 (65.9) | <0.001 |
| Second-line drugs | ||||
| Ethionamide | 303/705 (43.0) | 290/679 (41.7) | 13/26 (50.0) | 0.461 |
| Amikacin | 125/503 (24.8) | 13/366 (3.6) | 112/137 (81.8) | <0.001 |
| Kanamycin | 82/383 (21.4) | 4/280 (1.4) | 78/103 (75.7) | <0.001 |
| Capreomycin | 82/382 (21.5) | 4/280 (1.4) | 78/102 (76.5) | <0.001 |
| Ofloxacin | 372/512 (46.9) | 99/372 (26.6) | 140/140 (100.0) | <0.001 |
| Ciprofloxacin | 5/10 (50.0) | 5/9 (55.6) | 0/1 (0.0) | 0.292 |
| Moxifloxacin | 13/20 (0.0) | 8/14 (57.1) | 5/6 (83.3) | 0.260 |
| Levofloxacin | 4/9 (44.4) | 2/6 (33.3) | 2/3 (66.7) | 0.343 |
MDR-TB = multidrug-resistant TB.
n/N* = number of resistance patients/total of tested patients.
†Comparison between MDR/XDR-TB.