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. 2019 Nov 1;48(10):1285–1293. doi: 10.1097/MPA.0000000000001420

FIGURE 5.

FIGURE 5

erbB2 amplification influences colony-forming ability and response to cetuximab in pancreatic cancer cells. A, Among 10 pancreatic cancer cell lines, only SNU-2491 formed average 17 colonies 28 days after seeding. B, SNU-2491 was the only cell line that had evidently upregulated HER2 protein level compared with other established cell lines. C, Each cell lines were tested for the response of cetuximab. SNU-2491 was the only cell line that showed significantly inhibited growth rate in accordance with cetuximab treatment. D, SNU-2491 did not respond to trastuzumab despite of amplified HER2. E, The efficiency of cetuximab compared with trastuzumab in SNU-2491 was re-encapsulated with anchorage-dependent colony-forming assay.