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(A) bovine IVD (bIVD) treatment by MSCs in spatial separation (0.22 μm porous membrane). (B-C) No changes in Tie2 expression (0.8- ± 0.5-fold) and fraction of dead cells (1.0- ± 0.3-fold) relative to donor corresponding ctrl disc was found at day 5 (n = 5 bovine tails, 2 MSC donors). IVD indicates intervertebral disc; MSCs, mesenchymal stem cells.
