GABABR is functionally expressed at presynaptic loci at glutamatergic synapses onto both MSN subtypes in the NAc core. A, Representative traces of 50 ms ISI paired pulse eEPSCs obtained from D1(+)MSNs (blue circles) and D1(−) MSNs (open circles) at baseline and in the presence of BAC. Scale bars: top, 200 pA/50 ms; bottom, 100 pA/50 ms. BAC application increases PPR and (B) CV at D1(+) and D1(−) MSNs. C, E, Representative traces of TTX-insensitive mEPSCs pre- and post-BAC application at D1(+) MSNs (black) and D1(−) MSNs (gray). Scale bar, 20 pA/1 s. D, F, BAC decreases mEPSC frequency but not amplitude at D1(+) MSNs and D1(−) MSNs. Error bars indicate SEM. *p < 0.05.