Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 31;8:e52654. doi: 10.7554/eLife.52654

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019, Eichel et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Figure 8. — (A) Effects of hERG1a or hERG1b silencing on K_V4.2 channel mRNA expression levels detected by RT-qPCR (mean ±95% CI) in IPSC-CMs. A non-targeting shRNA (scrambled shRNA) is used as a control. (B) Effects of specific hERG1a or hERG1b silencing on K_V4.2 channel mRNAs expressed alone in HEK293 cells. (C) Representative family of traces show I_to in presence of control (upper) or hERG1b shRNA (lower). (D) Summary of steady-state current density vs. test potential shows effect of hERG1b shRNA (mean ±SE).

Figure 8—source data 1. KCND2 is not affected by the co-knockdown effect raw data for Figure 8A–B.

elife-52654-fig8-data1.xlsx^{(48.3KB, xlsx)}

DOI: 10.7554/eLife.52654.042

Figure 8—source data 2. Ito current is not affected by the silencing of hERG raw data for Figure 8D.

elife-52654-fig8-data2.xlsx^{(48.9KB, xlsx)}

DOI: 10.7554/eLife.52654.043