Comparison 3. Gabapentin and pregabalin versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Acute pain 0 to 6 hours	2	202	Std. Mean Difference (IV, Random, 95% CI)	‐0.62 [‐0.90, ‐0.34]
2 Acute pain at 24 hours	2	202	Std. Mean Difference (IV, Random, 95% CI)	‐0.78 [‐2.06, 0.51]
3 Acute pain at 48 hours	2	202	Std. Mean Difference (IV, Random, 95% CI)	‐0.02 [‐0.29, 0.26]
4 Additional analgesia requirement 0 to 24 hours	3	235	Std. Mean Difference (IV, Random, 95% CI)	‐0.37 [‐1.10, 0.35]
5 Nausea and vomiting	3	275	Risk Ratio (M‐H, Random, 95% CI)	0.51 [0.29, 0.89]