. 2019 Oct 20;39(10):1221–1226. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2019.10.14

2.

添加罗伊氏乳杆菌对小鼠炎症因子的影响

Effects of Lactobacillus reuteri on inflammatory cytokines in the intestinal tissues in the mice

Inflammatory cytokines	Control (n=8)	NEC (n=8)	NEC+ L. reuteri (n=8)	P
^aP < 0.05 vs Control group; ^bP < 0.05 vs NEC group.
RT-PCR
IL-1β	0.34±0.03	1.24±0.07^a	0.75±0.05^ab	< 0.001
TNF-a	0.24±0.04	1.31±0.18^a	0.42±0.06^b	< 0.001
ELISA
IL-1β (pg/mL)	394.87±12.50	555.09±11.41^a	448.72±14.90^ab	< 0.001
TNF-α (pg/mL)	68.00±3.74	83.00±3.30^a	68.44±2.39^b	0.004