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. 2019 Feb 18;23(4):1177–1186. doi: 10.1007/s11325-019-01797-4

Fig. 3.

Fig. 3

Intermittent hypoxia enhanced the RANTES-stimulated adhesion of monocytic THP-1 cells to vascular endothelial cells. Pretreated monocytic THP-1 cells with normoxia or intermittent hypoxia were activated by 30 ng/ml RANTES for another 18 h, and then processed for adhesion assay. a Photos represented for monocytic THP-1 cells after cell adhesion assay. Black arrow indicated the adhered cells. Scale bar = 100 μm. (Normoxia: without any treatment, Normoxia + RANTES: with RANTES stimulation only, Intermittent hypoxia: with intermittent hypoxia pretreatment only, Intermittent hypoxia + RANTES: with intermittent hypoxia pretreatment and RANYES stimulation.) b Statistical results from three independent experiments showed intermittent hypoxia treatment synergistically promoted the adhesive activity of monocytic THP-1 cells. (Data are presented as mean ± SEM; *p < 0.05 vs. Normoxia, p < 0.05 vs. Normoxia + RANTES, p < 0.05 vs Intermittent hypoxia)