Figure 4.

The detailed expression of p-Erk1/2. Representative images of p-Erk1/2 protein expression in liver cancer's corresponding (A) non-cancerous (NC) and (B) cancerous (C) regions. (C) Quantification of p-Erk1/2 expression (total, cytoplasmic, and nuclear expressions and the rate of nuclear localization) levels using multispectral image analysis in the liver cancer samples. (D) The ratio of “cancerous region/non-cancerous region” of p-Erk1/2 expression in two groups (well-differentiated group vs. moderately and poorly differentiated group). The red line indicates that the ratio is equal to 1. Scale bar: 200 or 50 μm. *, **Denote significant differences from the noncancerous region, or well-differentiated group with P < 0.05, 0.01, respectively.