Table 2.
Comparison of the first occurred nonfatal and fatal CVD events (study end point) between CPAP-treated and control patients
| CPAP-treated patients | Control patients | P value | ||
|---|---|---|---|---|
| (N = 1030) | (N = 1030) | |||
| Nonfatal | Nonfatal CVD events (N = 241) | 126 | 115 | 0.451 |
| Stroke confirmed by CT/MRI | 45 | 55 | 0.305 | |
| CAD diagnosed by angiography and invasively treated | 17 | 10 | 0.175 | |
| Angina pectoris | 42† | 19‡ | 0.003 | |
| Nonfatal myocardial infarction | 22§ | 31|| | 0.210 | |
| Fatal | Fatal CVD events (N = 101) | 22 | 79 | < 0.001 |
| Ischemic heart disease | 8 | 44 | ||
| Stroke | 4 | 6 | ||
| Cardiomyopathy | 3 | 10 | ||
| Aortic dissection/aortic aneurysm | 2 | 4 | ||
| Other causes* | 5 | 15 | ||
CPAP continuous positive airway pressure, CVD cardiovascular disease, CT computerized tomography, MRI magnetic resonance imaging, CAD coronary artery disease
*Cardiac arrhythmias, heart valve disease, atherosclerosis, hypertension, and thrombophlebitis of deep veins
†Of which eight diagnosed by angiography (unstable angina pectoris)
‡Of which four diagnosed by angiography (unstable angina pectoris)
§Of which 17 diagnosed by angiography
||Of which 15 diagnosed by angiography