Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 14;10:2650. doi: 10.3389/fimmu.2019.02650

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Liu, Huang, Hu, He, Li, Ran, Du, Fu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

IVX improved LPS-induced sickness behavior in mice. (A) Experimental design of a LPS-induced neuroinflammatory model. Mice were injected in the lateral ventricle with 5 μg STO-609 or 5 μg SR-18292 for 24 h, then treated with intraperitoneally injected IVX (10 mg/kg) daily for 3 consecutive days and then subcutaneously injected with LPS (0.33 mg/kg) for 24 h. (B,E) The changes in mouse body weight from before to after the experiment. (C,D,F,G) The locomotor activity of mice was measured via an open field test. Results are expressed as means ± SEM (n= 8–10, in each group). ^##p < 0.01, vs. control group; **p< 0.01 vs. LPS group; ^$p < 0.05 and ^$$p < 0.01 vs. IVX + LPS group.