Table 1.
Nanoplatforms examples and their characteristics.
Nanoplatforms | Biosafety | Size | Loading capacity | References | |
---|---|---|---|---|---|
Magnetic Nanoparticle | DOX IONPS | Low toxicity | 10–50 nm | High | Choi et al., 2012 |
Polymer-conjugates | DOX-GEM GADOLINIUM HPMA | Low toxicity | 20–70 nm | Good | Vilos and Velasquez, 2012 |
Nanovesicles | β(CD) SPIO Polymeric micelles | Really low toxicity | 10–70 nm | High | Liong et al., 2008; Bhojani et al., 2010 |
Dendrimers | asODN MNP PAMAM | Potential toxicity | 10–40 nm | High | Pan et al., 2007 |
Different nanoplatforms and the respective biosafety, size, and loading capacity.
DOX-conjugated, doxorubicin; PAMAM, poly(amidoamine); IONPs, iron oxide nanoparticles; DOX-GEM, gemcitabine (GEM), and doxorubicin (DOX); HPMA, N-2- hydroxypropylmethacrylamide; asODN, antisense oligodeoxynucleotides; MNPs, Magnetic Nanoparticles; SPIO, superparamagnetic iron oxide.