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. 2019 Nov 14;10:1178. doi: 10.3389/fneur.2019.01178

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Copyright © 2019 Shah, Li, Kury, Zeb, Khatoon, Liu, Yang, Liu, Yao, Khan, Koh, Jiang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of glutamate neurotransmission and synaptic changes in various ischemic models western blot analysis of GluR1, p-GluR1 (Ser845, Ser831), SNAP25, Synaptophysin. Densitometric analysis was expressed in relative to β-Actin (n = 5/group). ^θp < 0.05 relative to I/R MCAO, ^ηp < 0.05 between p-MCAO and Dia p-MCAO. *p < 0.05, ^#p < 0.05, and ^πp < 0.05 relative to sham group. ***p < 0.001, **p < 0.01, ^###p < 0.001, and ^##p < 0.01. ^θθshows significant difference of p-MCAO and Dia p-MCAO to I/R, and its value is p < 0.01, ^θθθshows significant difference of p-MCAO and Dia p-MCAO to I/R, and its value is p < 0.001, ^ππshows significant difference of I/R MCAO to sham, and its value is p < 0.01, ^πππshows significant difference of I/R MCAO to sham, and its value is p < 0.001, ^ηηshows significant difference between p-MCAO and Dia p-MCAO, and its value is p < 0.01.