Table 1.
Genes associated with relapse in uveal melanoma.
| Gene | HR | 95% CI | FDR | Location |
|---|---|---|---|---|
| PTP4A3 | 2.54 | (2.01 to 3.20) | <0.001 | 8q24.3 |
| JPH1 | 2.34 | (1.87 to 2.94) | <0.001 | 8q21.11 |
| ID2 | 0.48 | (0.39 to 0.6) | <0.001 | 2p25.1 |
| ANG | 0.42 | (0.33 to 0.55) | <0.001 | 14q11.2 |
| PRKDC | 1.97 | (1.61 to 2.41) | <0.001 | 8q11.21 |
| POP1 | 1.91 | (1.57 to 2.33) | <0.001 | 8q22.2 |
| RAB11FIP1 | 0.52 | (0.42 to 0.63) | <0.001 | 8p11.23 |
| CDC25B | 2.06 | (1.65 to 2.57) | <0.001 | 20p13 |
| CHAC1 | 1.97 | (1.59 to 2.43) | <0.001 | 15q15.1 |
| LPIN1 | 0.51 | (0.42 to 0.64) | <0.001 | 2p25.1 |
| CHD7 | 1.97 | (1.59 to 2.45) | <0.001 | 8q12.2 |
| VCPIP1 | 1.99 | (1.60 to 2.48) | <0.001 | 8q13.1 |
| ROPN1B | 0.50 | (0.40 to 0.62) | <0.001 | 3q21.2 |
| MTFR1 | 1.86 | (1.52 to 2.28) | <0.001 | 8q13.1 |
| MCM4 | 1.81 | (1.49 to 2.19) | <0.001 | 8q11.21 |
| COL9A3 | 1.88 | (1.53 to 2.31) | <0.001 | 20q13.33 |
| ASAP1 | 2.02 | (1.61 to 2.55) | <0.001 | 8q24.22 |
| SPIRE1 | 2.02 | (1.60 to 2.55) | <0.001 | 18p11.21 |
| TLCD1 | 1.83 | (1.50 to 2.24) | <0.001 | 17q11.2 |
| RAB2A | 1.80 | (1.48 to 2.18) | <0.001 | 8q12.1 |
Top 20 genes with lowest FDR shown (full results in the supplement) in a meta-analysis of univariable survival models against the expression of each individual gene.