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. 2019 Nov 20;9:312. doi: 10.1038/s41398-019-0650-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Amplitude of baseline motor-evoked potentials (MEP) for each group (in mV). b Corticospinal silent period duration (CSP) duration; c Results of paired-pulse stimulation protocols expressed in ratio from baseline. Significant differences were found on intracortical facilitation (ICF), short-intracortical inhibition (SICI), and long-interval cortical inhibition (LICI). Short-interval cortical facilitation (SICF) did not differ between groups. d Association between SICI and ICF in each group. A significant positive correlation was present in the FXS group, and significantly different from the one in the control group. Error bars indicate standard error of the mean.