Table 2.
Analysis of associations between rs11846556 genotype and chronic pain/MDD.
| Beta | SE | OR | p | FDR-adj. p | Additional adjuster | |
|---|---|---|---|---|---|---|
| (A) | ||||||
| CP (dichot.) | 0.015 | 0.004 | 1.02 | 2.63E-04 | 7.89E-04 | |
| CP (dichot.) | 0.017 | 0.008 | 1.02 | 0.048 | 0.096 | MDD (dichot) |
| MDD | 0.014 | 0.009 | 1.01 | ns | ||
| MDD | 0.011 | 0.010 | 1.01 | ns | CP (dichot) | |
| Beta | SE | p | FDR-adj. p | |||
|---|---|---|---|---|---|---|
| (B) | ||||||
| CPC | 0.018 | 0.004 | 7.26E-06 | 4.36E-05 | ||
| MDD severity | 0.014 | 0.009 | ns | |||
(A) results of logistic regression models with dichotomous chronic pain (CP(dichot.)) and major depressive disorder (MDD) variables as outcomes and SNP genotype as predictor. SE = standard error of the beta coefficient value, OR = odds ratio. Ns = non-significant (p > 0.05)
(B) results of ordinal regression models with chronic pain category and MDD severity variables as outcomes and SNP genotype as predictor. SE = standard error of the beta coefficient, ns = non-significant (p > 0.05)