Table 2.

Frequency of rare coding mutations in the CD36 gene in the French case, FREX control, gnomAD European global and control populations.

Variant	Number of heterozygous carriers in French cases (frequency %)	Number of heterozygous carriers in FREX controls (frequency %)	Number of heterozygous carriers in global gnomAD Europeans (frequency %)	Number of heterozygous carriers in control gnomAD Europeans (frequency %)	FREX P-value*	gnomAD global P-value*	gnomAD control P-value*
p.Pro191Leu	1 (0.27%)	1 (0.088%)	54 (0.035%)	18 (0.029%)	p = 1	p = 0.30	p = 0.24
p.Ala252Val	1 (0.27%)	0 (0%)	1 (0.00040%)	0 (0%)	p = 0.35	p = 0	p = 0
Total	2/184	1/566	55/77,061	18/31,413	p = 0.30	p = 0.0002	p = 0.00005

^*Yate’s chi-square test.