Table 3.

Fitted logistic regression model of prostate cancer overdiagnosis for patients with average comorbidities, ages 50–74 years

Covariate	Odds ratio	95% CI	P value
Intercept*	0.11	(0.11, 0.12)	<0.001
Age at diagnosis, y	1.13	(1.13, 1.13)	<0.001
PSA level, ng/mL	0.87	(0.86, 0.88)	<0.001
Gleason 7 vs 2–6	0.85	(0.82, 0.89)	<0.001
Age × PSA	1.00	(1.00, 1.00)	<0.001
Age × (Gleason 7 vs 2–6)	0.99	(0.99, 1.00)	<0.001
PSA × (Gleason 7 vs 2–6)	1.01	(1.00, 1.02)	0.05

^*Covariates were scaled so the intercept corresponds to a patient age 50 y with PSA 4 ng/mL and Gleason 2–6 at screen detection.