Table 3.

Report of the statistical significance (p-value) of the individual energy components between different types of NPs in Fig. 5 as a function of membrane excess areas

	Aex = 6%	Aex = 20%
Free energy
Rigid vs. rigid-tethered	8.3 × 10−5	0.0008
Rigid vs. flexible	0.001	4.8 × 10−6
Rigid-tethered vs. flexible	0.003	7.4 × 10−5
Entropy
Rigid vs. rigid-tethered	0.002	0.0002
Rigid vs. flexible	3.9 × 10−5	3.2 × 10−5
Rigid-tethered vs. flexible	0.001	0.0007
Enthalpy
Rigid vs. rigid-tethered	8.28 × 10−5	0.0008
Rigid vs. flexible	0.001	4.8 × 10−6
Rigid-tethered vs. flexible	0.003	7.4 × 10−5
Free energy per bond
Rigid vs. rigid-tethered	0.0001	0.0002
Rigid vs. flexible	0.0691	4.69 × 10−5
Rigid-tethered vs. flexible	0.005	0.0006
Entropy per bond
Rigid vs. rigid-tethered	0.81	0.5
Rigid vs. flexible	0.47	0.75
Rigid-tethered vs. flexible	0.026	0.006
Enthalpy per bond
Rigid vs. rigid-tethered	0.0001	0.0002
Rigid vs. flexible	0.069	4.86 × 10−5
Rigid-tethered vs. flexible	0.005	0.0006