TABLE 4.
Outcome Data Per Density Grouping
| Factor/Outcome | Overall (n = 701) | Density 1/2 (n = 487) | Density 3/4 (n = 214) | p-value |
|---|---|---|---|---|
| Margin width, invasive* | 0.009 | |||
| Negative (> 1 mm) | 622 (88.7%) | 444 (91.2%) | 178 (83.2%) | |
| Close (≤ 1 mm) | 46 (6.6%) | 25 (5.1%) | 21 (9.8%) | |
| Positive | 33 (4.7%) | 18 (3.7%) | 15 (7%) | |
| Margin width, DCIS | 0.31 | |||
| Negative (> 1 mm)† | 570 (81.3%) | 397 (81.5%) | 173 (80.8%) | |
| Close (≤ 1 mm) | 106 (15.1%) | 76 (15.6%) | 30 (14%) | |
| Positive | 25 (3.6%) | 14 (2.9%) | 11 (5.1%) | |
| Number of Re-excisions | 0.161 | |||
| 0 | 595 (84.9%) | 422 (86.7%) | 173 (80.8%) | |
| 1 | 98 (14%) | 60 (12.3%) | 38 (17.8%) | |
| 2 | 6 (0.9%) | 4 (0.8%) | 2 (0.9%) | |
| 3 | 2 (0.3%) | 1 (0.2%) | 1 (0.5%) | |
| Mastectomy performed‡ | 6 (0.9%) | 3 (0.6%) | 3 (1.4%) | 0.376 |
DCIS ductal carcinoma in situ
*
Width of closest margin, invasive component only
†
Width of closest margin, DCIS component only
‡
Mastectomy performed following attempted breast-conserving surgery