TABLE 2.
Accuracy of Post-NAC Axillary Exam, Ultrasound, and MRI in Detecting Residual Nodal Disease in cN+ Patients
| Clinical Exam | MRI | Ultrasound | |||||||
|---|---|---|---|---|---|---|---|---|---|
| PPV | NPV | Accuracy | PPV | NPV | Accuracy | PPV | NPV | Accuracy | |
| Javid (2010) n = 38 | - | - | - | 80.9% | 92.3% | - | - | - | - |
| Hieken (2013) n = 154 (MRI 88, US 106) | - | - | - | 75% | 42.5% | 60% | 71% | 56.8% | 65% |
| *Boileau (2014) n = 153 | 89% | 38% | 45% | - | - | - | 81% | 48% | 62% |
| Steiman (2016) n = 135 | - | - | - | 93% | 26% | 48% | - | - | - |
| Hyun (2016) n = 115 | - | - | - | 96.8% | 65.5% | 74% | - | - | - |
| *Schwentner (2017) n = 651 (US 299, CE 352) | 65.3% | 46.6% | - | - | - | - | 77.5% | 50.3% | |
| Weber (2017) n = 65 | - | - | - | 67% | 66% | - | - | - | - |
PPVpositive predictive value, NPVnegative predictive value, US ultrasound, CE clinical exam
All studies of include patients with both positive and negative axillary clinical exam
*
Analyses of prospective trial data