Comparison 1. Cyclosporin (CSA) versus placebo/no treatment.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Complete remission	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 All renal pathologies	4	74	Risk Ratio (M‐H, Random, 95% CI)	3.50 [1.09, 11.20]
1.2 FSGS	3	58	Risk Ratio (M‐H, Random, 95% CI)	3.14 [0.97, 10.18]
2 Complete or partial remission	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 All renal pathologies	4	74	Risk Ratio (M‐H, Random, 95% CI)	3.15 [1.04, 9.57]
2.2 FSGS	2	49	Risk Ratio (M‐H, Random, 95% CI)	2.66 [0.85, 8.31]
3 Adverse events	3		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
3.1 Worsening of hypertension	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.2 Infection	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.3 ESKD	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]