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. 2019 Nov 21;2019(11):CD003594. doi: 10.1002/14651858.CD003594.pub6

Comparison 6. Oral cyclophosphamide (CPA) versus prednisone/placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Complete remission 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.1 All renal pathologies 2 84 Risk Ratio (M‐H, Random, 95% CI) 1.06 [0.61, 1.87]
1.2 FSGS 2 63 Risk Ratio (M‐H, Random, 95% CI) 1.01 [0.43, 2.37]
2 Complete or partial remission 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.1 FSGS 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
3 Treatment failure 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4 Adverse events 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.1 Death (all causes) 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
4.2 Hypertension with seizures 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
4.3 Cystitis 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
4.4 Bone marrow suppression 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]