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. 2019 Nov 20;9:17207. doi: 10.1038/s41598-019-53627-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Intravitreal administration of SCH 58261 inhibits retinal thinning in diabetic animals. Retinal thickness was calculated after layer segmentation in OCT images. (A) Representative OCT images at eight weeks of diabetes. (B) The results were normalized to baseline. Wilcoxon matched-pairs signed rank test. GCL: ganglion cell layer; INL: inner nuclear layer; ONL: outer nuclear layer; IS-OS: photoreceptor inner and outer segments. Scale bars: 50 µm.