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. 2019 Oct 5;47(21):11114–11131. doi: 10.1093/nar/gkz858

Figure 6.

Figure 6.

Deletion of p150 impairs chromatin dynamics during ESC differentiation. (A) Representative browser tracks showing H3K27me3 and H3K4me3 at the Oct4 and Nanog loci before (ESC) and after (EB, day 7 EB) differentiation. (B–G) Relative levels of H3K27me3 and H3K4me3 between p150 WT and KO cells at the promoters of gene groups identified in Figure 2C. H3K27me3 for Group 1 (B), Group 2 (D), Group 3 (F) and Group 4 (H); H3K4me3 for Group 1 (C), Group 2 (E), Group 3 (G) and Group 4 (I). The y-axis represents the log2 ratio of ChIP-seq reads. The P-values were calculated using Wilcoxon test.