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. 2019 Jun 12;124(5):749–767. doi: 10.1093/aob/mcz100

Fig. 4.

Fig. 4.

A model of strigolactone perception and signal transduction pathway. ① SL binds in the catalytic cleft of D14 and induces a destabilization/conformational change in D14; ② SL-induced destabilization of D14 facilitates D14 interaction with SCFD3; ③ SCFD3-D14 recruits a target protein (e.g. D53 or SMXLs); ④ D53/SMXLs undergo polyubiquitination; ⑤ proteasomal degradation; ⑥ D14 deactivates the bound SL molecule by hydrolytic cleavage of the enol–ether bridge and releases the ABC and D rings.