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. 2019 Nov 12;10:1188. doi: 10.3389/fneur.2019.01188

Figure 2.

Figure 2

(A) The corticoreticular pathway (CRP) (blue color) and corticospinal tract (CST) (red color) were reconstructed in both hemispheres [a—centrum semiovale (CS) level, b—corona radiata (CR) level, c—posterior limb of the internal capsule (PL) level]. (B) The regions of interest (ROIs) (blue color) were set for the CRP (seed—reticular formation of the medulla, first target ROI—midbrain tegmentum, second target ROI—Brodmann's area 6). The ROIs (red color) were set for the CST (seed ROI—anterior portion of lower pons, target ROI—Brodmann's area 4). (C) Landmarks used in determining the location of the CRP and CST (left and middle columns). The probabilistic maps for the CRP and CST were superimposed on images of a subject (right column). Line I: the midline between the right and left hemispheres for measurement of mediolateral distance. Line II: the horizontal line from the most medial point of the central sulcus to the midline as the reference line for the anteroposterior direction. Line III: the horizontal line that passes through the anterior end of the lateral ventricle for the reference line for the anteroposterior direction. Line IV: the horizontal line from the middle point at the genu of the internal capsule [Reprinted with permission from Jang and Seo (25)].