Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 16;47(21):11044–11056. doi: 10.1093/nar/gkz906

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — Vectorial folding of hTel28. (A) Schematic of unfolding of a hTel28-duplex via Rep-X and subsequent folding of hTel28 into GQ. (B) E histograms of hTel28-duplex in the Rep-X unbound (top) and bound (middle) states, and after Rep-X unwinding of the duplex in presence of ATP and MgCl₂ (bottom). The curve represents Gaussian fit to the folded GQ population. E histogram of hTel28.1 in the unwinding buffer is superimposed in light blue (bottom). (C) Representative single molecule trajectory showing unwinding of the duplex and folding of GQ (30 ms integration time).