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. 2019 Oct 17;47(21):11355–11367. doi: 10.1093/nar/gkz911

Figure 6.

Figure 6.

Correlation of R882H* flanking sequence preference with the flanking sequence context of CpG sites specifically hypermethylated in R882H containing AML (31). (A) Enrichment or depletion of R882H*preferred flanks in the different hypermethylated groups. Flanks strongly preferred by R882H have a relative preference of 100 disfavored flanks have a preference of 0. (B) Correlation of the enrichment of flanks in the Top-500 and Top-1000 group with the R882H* preference. (C) Compilation of r-values and corresponding P-values of the correlation of the R882H* flanking sequence preferences with the enrichment of flanks in the different groups of hypermethylated CpG sites.