REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
anti-γH2AvD	GeneTex	RRID: AB_11165216
anti-8-oxo-dG	Trevigen	RRID: AB_1857195
anti-polyADPribose	BD Biosciences	RRID: AB_394263
anti-GFP	Abcam	RRID: AB_304896
anti-RFP	MBL	RRID: AB_591278
Streptavidin-Cy3	Jackson Immunoresearch	RRID: AB_2337244
Biotinylated anti-mouse	Vector labs	RRID: AB_2687893
Biotinylated anti-rabbit	Vector labs	RRID: AB_2336201
Anti-DIG AP-conjugated antibody	Sigma-Aldrich	RRID: AB_2734716
Bacterial and Virus Strains
Library Efficiency DH5α Competent Cells	Invitrogen	#18263012
Chemicals, Peptides, and Recombinant Proteins
Vectashield	Vector labs	RRID: AB_2336789
Heptane	Sigma	#246654
Formaldehyde 37%	Sigma	# 47608
Methanol	Sigma	# 34860
Hydrogen peroxide	Sigma	#95321
Triton-X	Sigma	#X-100
Tween-20	Sigma	# P9416
Trizol	Invitrogen	#15596026
10S Voltalef oil	VWR	#24627.188
DHE	Invitrogen, Molecular Probes	#D11347
H2DCF	Invitrogen, Molecular Probes	#D399
PBS	Sigma	#P5493
Bovine serum albumin	Sigma	#A3983
Proteinase K	Invitrogen	#25530049
Glycine	Sigma	#410225
Denhardts solution	Invitrogen	#750018
NBT	Roche	#11383213001
BCIP	Roche	#11383221001
Durcupan	Sigma	#44610
Critical Commercial Assays
RNeasy Mini Kit	QIAGEN	# 74104
Thermo Scientific Maxima First Strand cDNA Synthesis Kit	Thermo Scientific	# K1641
PowerUp SYBR Green Supermix	Applied Biosystems	#A25741
Experimental Models: Organisms/Strains
Drosophila: ubiquitous-moesin-GFP	[49]	N/A
Drosophila: serpent-Gal4	[50]	N/A
Drosophila: UAS-GFP	Bloomington Drosophila Stock Center	RRID: BDSC_6874
Drosophila: dEcadherin-GFP	Kyoto Stock Center	#109007
Drosophila: His2Av-mRFP1	Bloomington Drosophila Stock Center	RRID: BDSC_23651
Drosophila: ARE-GFP	[23]	N/A
Drosophila: GstD-ARE:GFP	[22]	N/A
Drosophila: da-Gal4	Bloomington Drosophila Stock Center	RRID: BDSC_55851
Drosophila: UAS-moesin-mCherry	[2]	N/A
Drosophila: OregonR	Bloomington Drosophila Stock Center	RRID: BDSC_2376
Drosophila: UAS-Gadd45	[26]	N/A
Drosophila: UAS-dNrf2	[22]	N/A
Drosophila: UAS-Gadd45-RNAi	Bloomington Drosophila Stock Center	RRID: BDSC_35023
Drosophila: UAS-dNrf2-RNAi	[22]	N/A
Drosophila: UAS-dNrf2-RNAi	Bloomington Drosophila Stock Center	RRID: BDSC_40854
Drosophila: e22c-Gal4	Bloomington Drosophila Stock Center	RRID: BDSC_1973
Drosophila: UAS-gcamp3	[17]	N/A
Drosophila: TRE-GFP	[23]	N/A
Drosophila: UAS-catalase	Bloomington Drosophila Stock Center	RRID: BDSC_24621
Drosophila: UAS-Duox-RNAi	[51]	N/A
Drosophila: UAS-trpm-RNAi	Bloomington Drosophila Stock Center	RRID: BDSC_31672
Drosophila: UAS-basket-DN	Bloomington Drosophila Stock Center	RRID: BDSC_6409
Drosophila: srp3	[27]	N/A
Drosophila: srpAS	[27]	N/A
Drosophila: UAS-reaper	Bloomington Drosophila Stock Center	RRID: BDSC_5824
Oligonucleotides
dNrf2 F-primer CTGCATCGTCATGTCTTCCAGT	Eurofins Genomics	N/A
dNrf2 R-primer AGCAAGTAGACGGAGCCAT	Eurofins Genomics	N/A
Gadd45 F-primer GGTACTGCTGGAGGCCTTTT	Eurofins Genomics	N/A
Gadd45 R-primer CGCAGTAGTCGACTAGCTGG	Eurofins Genomics	N/A
Rpl32 F-primer AGCATACAGGCCCAAGATCG	Eurofins Genomics	N/A
Rpl32 R-primer TGTTGTCGATACCCTTGGGC	Eurofins Genomics	N/A
Recombinant DNA
RE38191 cDNA clone	BDGP	# FBcl0207762
Software and Algorithms
GraphPad Prism V6.01	GraphPad Software	https://www.graphpad.com/scientific-software/prism/
ImageJ/Fiji	National Institutes of Health	https://imagej.nih.gov/ij/
Volocity	PerkinElmer	https://www.perkinelmer.com/lab-products-and-services/resources/cellular-imaging-software-downloads.html
Photoshop	Adobe	https://www.adobe.com/uk/products/photoshop.html
Illustrator	Adobe	https://www.adobe.com/uk/products/illustrator.html