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Unilateral ureteral obstruction (UUO) induces tubular remodeling in the renal cortex and medulla after 7 days. (A) Haematoxylin–eosin staining in the renal cortex and medulla (scale bar, 100 µm). Black arrows show the increase of tubule interstitial space, while black asterisks show tubular dilation. Quantification of tubule diameter in the (B) cortex and (C) medulla of Sham and UUO groups. Mann–Whitney statistic test. *P 0.05 vs. Sham group (n = 5).
