Table 1.
Data homogeneity verification with respect to the reference study.
| Controls (n = 5) |
Controls (n = 30)a |
P value | |
|---|---|---|---|
| Median (Q1; Q3) | Median (Q1; Q3) | ||
| TRP µg/mL | 9.07 (7.08; 11.81) | 10.25 (8.99; 11.46) | .385 |
| KYN µg/mL | 0.43 (0.33; 0.45) | 0.38 (0.28; 0.46) | .587 |
| 5HTP µg/mL | 0.05 (0.04; 0.06) | 0.06 (0.04; 0.08) | .153 |
| 5-HT µg/mL | 0.04 (0.02; 0.07) | 0.02 (0.01; 0.03) | .057 |
| IDO1 activity | 40.35 (34.82; 57.18) | 38.27 (29.27; 48.52) | .436 |
| TPH1 activity | 5.09 (3.31; 6.16) | 5.68 (3.96; 6.928) | .564 |
Abbreviations: 5HTP, 5-hydroxy-tryptophan; IDO1, indoleamine 2,3-dioxygenase 1; KYN, kynurenine; TPH1, tryptophan hydroxylase 1; TRP, tryptophan; 5-HT, serotonin
New recruited control samples have been compared to those previously analysed.
a
Data retrieved from the reference study.