Skip to main content
. 2019 Nov 4;4(21):18948–18960. doi: 10.1021/acsomega.8b03100

Figure 10.

Figure 10

Analysis of amphipathic groove. Conservation of the 14-3-3 ζ amphipathic groove was confirmed by the anisotropic model, as described in (70). Whereby, ANM2.1 was utilized to analyze energy deformations occurring in the parental 14-3-3 ζ docking protein (A), SYN-AI-1 (B), SYN-AI-2, (C) and synthetic protein SYN-AI-3 (D). To further verify the conservation of the amphipathic groove, ANM2.1 was also utilized to predict parental and synthetic 14-3-3 ζ docking protein solvent accessibility (E).