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. 2019 Nov 20;7:312. doi: 10.1186/s40425-019-0781-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — CALR expression positively correlate with the frequency of mature DC-LAMP⁺ DCs and CD20⁺ B cells. a Representative images of DC-LAMP and CD20 immunostaining. Scale bar = 50 μm. b Density of DC-LAMP⁺ cells and CD20⁺ B cells in TME of CALR^Lo versus CALR^Hi HGSCs (n = 82). Box plots: lower quartile, median, upper quartile; whiskers, minimum, maximum. OS of HGSC patients (study group 1) who did not receive neoadjuvant chemotherapy, upon stratification based on median expression of CALR and density of DC-LAMP⁺ cells (c) or CD20⁺ B cells (d)