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. 2019 Nov 21;20:636. doi: 10.1186/s13063-019-3728-2

Table 1.

PICO research question of the arriba-PPI trial

PICO-Item Research question
P (patient) Patients aged ≥ 18 years regularly using PPIs over ≥ 6 months in primary care
I (intervention) GPs of enrolled patients with access to the arriba-PPI tool
C (comparison) GPs of enrolled patients without access to the arriba-PPI tool providing care as usual
O (outcome) Cumulated defined daily doses of PPI per study patient after 6 months