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. 2019 Nov 20;19:218. doi: 10.1186/s12890-019-0938-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — The effect of secreted Hsp90α on asthmatic downstream pathway factors and the impact of 1G6-D7 on HDM-induced activation of AKT, ERK, and P38. a:The activation of LRP-1, p-AKT (Thr 308), p-ERK1/2 and p-P38 in normal 16HBE cells were evaluated by western blots. Data shown are means±SD, (*P < 0.05 vs the control group,* ^#P < 0.05 vs the HDM group,n = 3). b: The activation of LRP-1, p-AKT (Thr 308), p-ERK1/2 and p-P38 in Hsp90α-knockdown cells were evaluated by western blots. Data shown are means±SD, (*P < 0.05 vs the control group,* ^#P < 0.05 vs the HDM group,n = 3)